Categories
Medical Sciences (Anatomy Pharmacology etc.) Physiology

What receptor do you think muscarine binds to in the ANS?

Required Resources
Read/review the following resources for this activity:
• Textbook: Saladin, K. S. (2019). Anatomy & physiology: The unity of form and function (9th ed). McGraw-Hill
•Minimum of 1 scholarly source
• George, P. & Hegde, N. (2013). Case Report: Muscarinic toxicity among family members after consumption of mushrooms Links to an external site.. Toxicology International, 20(1), 113-115.
Scenario/Summary
Four individuals presented to the ER with several signs and symptoms (see table 1). While taking their history, you ask if they’ve recently ingested anything. At first, they didn’t claim anything but then one remembered they went mushroom hunting and added it to a stew. You’re truffle hunting skills paid off when you identified the mushroom from their photo of it as Amanita Muscaria, a mushroom containing the neurotoxin muscarine.
Deliverables
Review the article above, answer the following questions and save your responses in a Microsoft Word document. Provide a scholarly resource in APA format to support your answers.
Four individuals presented to the ER with several signs and symptoms (see table 1).
1. Looking at the signs and symptoms, you notice that one of the two branches of the autonomic nervous system (ANS) is highly upregulated. Which one is it? Name three signs or symptoms that clued you in on it and why.
2. What receptor do you think muscarine binds to in the ANS? What neurotransmitter usually binds to the receptor?
3. At first, it seemed odd that three out of four of your patients were sweating. It makes sense now that you know what they ate. Why?
4. Treatment for this issue includes the use of atropine. Atropine is anticholinergic. Define anticholinergic and determine why you would use it in this case.